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MLB DFS Picks: Spotlight Hitters & Stacks for Wednesday, April 28th

Eric MacPherson



MLB DFS Picks & Stacks for Yahoo, DraftKings + FanDuel daily fantasy baseball lineups, including the Astros and Blue Jays | Wednesday 4/28/21

MLB DFS action on Wednesday, April 28, features 15 games across six slates with giant contests on Yahoo, DraftKings and FanDuel. Stacks like the Astros and Padres are offering massive upside on this supersized slate, and here we will break down the bats that have prime pitching matchups worth targeting.

Be sure head over to the Awesemo MLB DFS HOME PAGE for all of the best written daily fantasy baseball content, including daily article like Spotlight Pitchers, MLB DFS Tournament Strategy and MLB Cheat Sheets for all the major DFS sites.

MLB DFS Picks: Spotlight Hitters and Stacks, Wednesday, April 28th

Yahoo Stack of the Day: Toronto Blue Jays vs. RHP Erick Fedde — 5.5 implied runs

The Blue Jays, still playing in their spring training ballpark in Florida, scored 14 runs last night, and through seven games there this season, they have averaged 10.4 runs. Erick Fedde gets by with smoke and mirrors and should not be in the starting rotation. He has below-average strikeout stuff, allows too many walks and is susceptible to home runs. This is a recipe for disaster from the Nationals’ perspective, or a delicious and tasty treat for the Blue Jays. On Yahoo, Cavan Biggio ($13), Rowdy Tellez ($10), Marcus Semien ($14) and Lourdes Gurriel ($8) will allow gamers to focus on two top-shelf pitchers or a high-end main stack. Toronto should gain traction throughout the day as more content comes out. However, there are not many Yahoo-specific fantasy articles, which is a bonus for the gamers playing there.


Early Slate

Miami Marlins vs. RHP Zack Godley — 4.4 implied runs

Zack Godley will likely be called up to replace lefty Brett Anderson, who is heading to the injured list with a hamstring injury. The last time Godley pitched was during the short season when he made seven starts for the Red Sox, who were in dire straits. Across 28.2 innings over eight appearances, Godly was crushed for an 8.16 ERA while allowing nearly two base runners per inning and 17 total extra-base hits.

Gamers can look to anyone with power from the Marlins, with Adam Duval and Corey Dickerson leading the way. Jesus Aguilar is very familiar with the hitting conditions in American Family Field, having spent five seasons with the Brewers. He generally fares well against same-handed hurler0s, and he is definitely a threat for a longball this afternoon. Garrett Cooper will likely be in the middle of the order, and there is a chance that Jon Berti will be promoted to lead off if Jazz Chisholm is held out with his hamstring injury suffered last night.

Evening Slate

Houston Astros vs. RHP Justin Dunn — 5.0 implied runs

While he is a hard-thrower, Dunn’s rate of 6.85 BB/9 over his 67 innings in The Show is very alarming, and his 7.66 K/9 rate is not nearly enough to offset things. The low groundball rate of 34.8% and xFIP of 6.36 indicate that crooked numbers are likely to be handed out by opposing teams regularly.

The Astros are back to full health. The top targets will always be Alex Bregman and Yordan Alvarez, but in today’s matchup everyone is in play, particularly since weather will not be a concern in this game. The Mariners bullpen is in the bottom third of the league by most metrics, and their lone lefty, Anthony Misiewicz, threw 20 pitches last night. Feel free to mix and match with Michael Brantley, Yuli Gurriel, Carlos Correa, Jose Altuve, Kyle Tucker and whoever is behind the dish.

Late Slate

San Diego Padres vs. RHP Taylor Widener — 5.4 implied runs

This will be the third time that Taylor Widener has made this article in April. Through four starts he has actually been better than projected this spring when there was talk of making him a reliever. The Diamondbacks need starting pitchers, so they are giving Widener a long look. Across his 21.1 innings, he has a 2.82 ERA and an excellent 2.42 BB/9. However, advanced metrics are not smiling on him, with a 5.99 xERA and a 4.75 xFIP. The 1.61 HR/9 is alarming, and he has lucked out with an 88.2% strand rate, which is well above the 72% league average.

Tonight is going to be a pleasant evening in Arizona, with game-time temperatures in the mid-80s and a 7 to 9 mph breeze out to center field and the roof scheduled to be open. The lefties from the Padres will be the priority targets, with Eric Hosmer, Trent Grisham and Jake Cronenworth leading the way. Cronenworth and switch-hitting Jurickson Profar both provide some excellent salary relief, though they will be in the bottom third of the order.

Gamers can connect full stacks with Fernando Tatis Jr., Manny Machado and Wil Myers, who are tremendous hitters against pitchers of either handedness. While Arizona used three relievers last night, the other five have not pitched since Friday. There are four righties, and Alex Young is the lone southpaw. The Diamondbacks bullpen ranks in the bottom third of the league, so San Diego should be a priority stack on all slates Wednesday.

Final Thoughts for the Wednesday, April 28th MLB DFS Slate

Watch the weather in several locations for precipitation issues, including the games in Cleveland, St. Louis, Chicago, Pittsburgh, Baltimore and New York. Keep in mind that salaries and scoring formats differ across the various fantasy sites, and a home run play on Yahoo may be a below-average MLB DFS pick on DraftKings or FanDuel.

Eric "EMac" MacPherson won the 2007 Fantasy Baseball grand prize (trip for two to the MLB All-Star game) in the Roto format on ESPN. He won again in 2008, this time in the H2H format. As one of the early adopters of daily fantasy sports, EMac has been providing content for baseball and basketball as well as both professional and college football since 2012 for a variety of websites including DraftKings Playbook, FanVice, RotoWorld, Daily Fantasy Bootcamp, and RotoGrinders. He is well into his third decade of fantasy sports and has a wealth of knowledge and experience. Follow him on Twitter @EMacDFS or contact EMac by emailing

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