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NFL DFS First Look: Week 10 DraftKings & FanDuel Picks

Matt Gajewski

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Optimal NFL DFS picks for Week 11 Thursday Night Football Showdown lineups on DraftKings & FanDuel from Awesemo's lineup optimizer & projections

The NFL season continues to Week 10 with a full slate of NFL DFS action provided by DraftKings and FanDuel. This piece will examine the NFL DFS slate early in the week to find potential NFL DFS picks that will return the most value. Based on the salaries released by both DraftKings and FanDuel, we will go over some of the best Week 10 NFL DFS picks, but keep an eye on the news as the week progresses. A value play early in the week could turn into a bust chalk play due to injury or COVID-related illness. The best way to stay plugged in for all the news and notes throughout the week is by catching all the Awesemo NFL DFS Strategy and Picks shows on the Awesemo YouTube Channel.

NFL First Look: Week 10 NFL DFS Picks

Quarterbacks

Justin Herbert, MIN vs. LAC ($7,300 DraftKings, $8,000 FanDuel)

Coming off a 356-yard passing performance against Philadelphia last week, Justin Herbert looks like a solid option again in Week 10. The Chargers face off against the Vikings as 2.5-point favorites in a game with a 52 total. Herbert is completing 66.1% of his passes for 7.4 yards per attempt. He has also eclipsed 300 yards on four occasions, giving him excellent upside. Minnesota ranks 19th in yards allowed per pass attempt, giving Herbert an exploitable matchup. Look for him to continue his hot streak in Week 10.

Dak Prescott, ATL vs. DAL ($6,900 DraftKings, $8,100 FanDuel)

Dak Prescott threw for 232 yards on 39 attempts as the Cowboys fell 30-16 to the Broncos. Prescott did most of his damage in garbage time, but this gives him an affordable price. The Cowboys are 8.5-point favorites over the Falcons, who have one of the worst defenses in football, and Prescott has been efficient over a larger body of work. On the year he is completing 69.4% of his passes for 8 yards per attempt. This includes three games over 300 yards. Prescott looks like a strong option in a bounce-back spot in Week 10.

Carson Wentz, JAX vs. IND ($5,900 DraftKings, $7,500 FanDuel)

Carson Wentz has been up and down to start 2021. He is completing 63.3% of his passes for 7.3 yards per attempt. However, he is one of the few pay-down options as the quarterback position with a strong implied team total. The Colts are 10-point favorites over the Jaguars, who rank 26th in yards passing allowed, creating a strong environment for Wentz. While the Colts run the risk of riding the run in a positive game script, Wentz still is a solid pay-down option.

Running Backs

Ezekiel Elliott, ATL vs. DAL ($7,000 DraftKings, $8,000 FanDuel)

Ezekiel Elliott salvaged his horrible start against Denver in garbage time. He is still affordable across DFS platforms and draws a much better matchup this week against the 4-4 Falcons. Elliott continues to work well ahead of Tony Pollard and has a solid role in the receiving game. Prior to last week’s 13-touch game, Elliott had exceeded 20 touches in each of his prior five games. Betting on an explosive Dallas offense in a rebound spot makes sense.

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James Conner, CAR vs. ARI ($6,300 DraftKings, $7,000 FanDuel)

Chase Edmonds is expected to miss time with a high ankle sprain. In his place, James Conner handled 21 carries for 96 yards and five catches for another 77 yards against the 49ers last week. Conner already received a majority of the goal-line work and now could be the team’s bell-cow back. Arizona is a 10-point favorite over the Panthers in a game with a 45.5-point total. Even if Kyler Murray cannot quite return from injury, Conner’s volume should keep him in the cash conversation this week.

Devin Singletary, BUF vs. NYJ ($4,700 DraftKings, $6,000 FanDuel)

Devin Singletary saw a majority of Buffalo’s running back work after Zack Moss left with a concussion. Singletary only managed 15 touches, but Buffalo lost an anomalous game to Jacksonville by a score of 9-6. Buffalo had previously been one of the more efficient offenses in football, pointing to better days ahead. This week the Bills are 13-point favorites over the Jets, pointing to positive game script for Singletary. If Moss misses this game, Singletary could become the punt running back of choice in DFS.

Wide Receivers

Davante Adams, SEA vs. GB ($7,900 DraftKings, $8,700 FanDuel)

Aaron Rodgers‘ status for Week 10 is unknown at this point, but he at least has a chance to play. Without Rodgers last week, Davante Adams turned 14 targets into an inefficient six catches for 42 yards with Jordan Love at the helm. Adams has an elite 35.2% target share when healthy this year, making him a distinct value at this price. The Packers draw the Seahawks as 5-point favorites this week in a game with 49.5-point total. Adams already has three games over 100 yards this year and should return to form as long as Rodgers returns.

Keenan Allen, MIN vs. LAC ($7,000 DraftKings, $7,200 FanDuel)

For those looking at Chargers stacks, Keenan Allen is too cheap across DFS platforms. After Mike Williams shot out to a quick start, Allen has reasserted himself as Herbert’s favorite target. Allen is coming off back-to-back 11-target games, and last week he eclipsed 100 yards receiving for the third time this year. Allen now has 82 targets to 66 for Williams. While Williams still has the air yards edge, Allen has five more targets in the red zone. With Los Angeles projected to score near the top of the league in Week 10, targeting Allen in stacks is a strong play.

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Amari Cooper, ATL vs. DAL ($6,200 DraftKings, $7,300 FanDuel)

Amari Cooper saw his price rise despite recording two receptions for 37 yards on five targets. The Cowboys were down 30-0 to Denver at one point, causing Cooper to be removed from the game entirely. On the year Cooper has a 21% target share and 29% air yards share in an explosive Dallas offense. He has two games of over 100 yards receiving and should benefit from a better matchup. Cooper is still cash viable and a strong stacking option for those rostering Prescott.

Tight Ends

Kyle Pitts, ATL vs. DAL ($5,800 DraftKings, $6,900 FanDuel

This week’s tight end slate is barren without Travis Kelce, Darren Waller or George Kittle. This leaves Kyle Pitts at the top of the position. While Atlanta pulled off an upset victory New Orleans last week, they are 8.5-point underdogs to Dallas. Without Calvin Ridley, Pitts has emerged as Atlanta’s leading pass catcher. While Pitts only has 75 yards receiving over the last two weeks, he still leads the team in target share (23%). Pitts already has a pair of 100-yard games this year, displaying upside on par with the elite options at the position. Pitts also plays most of his snaps from the slot or out wide, acting as a true wide receiver. With the ownership falling, this could be a strong time to buy back into Pitts.

Dan Arnold, JAX vs. IND ($3,500 DraftKings, $5,100 FanDuel)

While Dan Arnold plays for one of the worst teams in the NFL, negative game script has treated him kindly. Arnold now has at least five targets in four straight games, including at least seven in three of the four. This has not led to much upside, and Arnold still has not scored this year. However, it provides an excellent floor at a cheap price. This week Arnold and the Jaguars are 10-point underdogs to the Colts in a game with a 47.5-point total. While the upside in lacking, most of the elite tight ends are off the slate. Even a moderate price-adjusted score could be enough from Arnold.

Tommy Sweeney, BUF vs. NYJ ($2,600 DraftKings, $4,600 FanDuel)

Buffalo is coming off a brutally inefficient loss at the hands of the Jaguars last week. Dawson Knox is still recovering from a hand injury, locking Tommy Sweeney into his role. In the Bills’ last two games, Sweeney has played on 84.3% of the snaps. While this has only amounted to six targets, Buffalo’s offense has struggled in this span. With a winnable matchup against the Jets on deck, Sweeney can be used as a pure punt option.


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View our DraftKings NFL DFS rankings and our FanDuel NFL DFS ownership rankings. We also have NFL single-game projections and showdown ownership projections. If you’re interested in other top NFL DFS plays today for multiple game slates, head over to NFL DFS ownership projections, Awesemo's NFL Data Central, NFL daily fantasy football rankings, and NFL stacks. Take a look at our depth charts for NFL games, starting lineups and inactive player list.

Matt Gajewski graduated from the University of Wisconsin with a degree in Economics. Matt has worked in the fantasy industry for the past four years, focusing on DFS and Sports Betting. Matt specializes in NFL, College Football, College Basketball, XFL, and MMA. With GPP victories across the major sports, Matt also qualified for the DraftKings 2020 Sports Betting Championship and won a seat to the College Basketball Tourney Mania final.

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