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How to Bet Rams vs. Cardinals Monday Night Football Tonight

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To cap off NFL Week 14, we have a Monday Night Football matchup between two NFC West rivals in the Los Angeles Rams and Arizona Cardinals. Anything could happen in these divisional games, making this an interesting NFL betting matchup tonight. The following Rams vs. Cardinals NFL betting picks preview will provide the current odds, betting trends and best NFL bets for the Week 14 Monday Night Football matchup.

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NFL Best Bets & Odds: Week 14 Monday Night Football

Los Angeles Rams vs. Arizona Cardinals
Date: Monday, Dec. 13, 2021
Time: 8:15 p.m. EST
Venue: State Farm Stadium — Glendale, Ariz.
Coverage: ESPN

Desperation mode is setting in for the Rams, who are fighting for a wild card spot. These have lost three of their past four games, with the only win coming against the Jaguars. Matthew Stafford is not healthy, the offense seems to have lost its chemistry as soon as Robert Woods got hurt, and the defense continues to get bullied. This could be a statement game. However, the statement may not be positive.

The Cardinals returned Kyler Murray and DeAndre Hopkins to the lineup last week, and they were able to tough out a win against the Bears. Yes, Arizona has the best record in the NFL. However, they play to their opponent’s skill level no matter how low of a skill level it is, and that is a dangerous game to play. They did easily win in the first matchup against the Rams, 37-20, however.

Rams vs. Cardinals Betting NFL Picks + Odds Shopping

Using Awesemo’s OddsShopper Tool, we can easily compare the NFL odds for Rams vs. Cardinals betting across the major sportsbooks. Make sure to check out the OddsShopper tool yourself to get the most up-to-date odds.

Rams vs. Cardinals NFL Betting Trends

  • Los Angeles is 5-7 against the spread this season.
  • The over is 6-5-1 for the Rams season.
  • Arizona is 9-3 against the spread this season.
  • The over is 6-6 for the Cardinals this season.

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Rams vs. Cardinals Betting Stats

  • The Rams are averaging 28 points per game this season (No. 5 in the NFL).
  • The Rams are surrendering 22.5 points per game this season (T-No. 17 in the NFL).
  • Arizona is averaging 28.6 points per game this season (No. 3 in the NFL).
  • Arizona is surrendering 18.7 points per game this season (No. 4 in the NFL).

Rams vs. Cardinals NFL Best Bet

We are using the new OddsShopper to figure out the best bet for Monday Night Football. According to the model, betting the Cardinals -2 is the best bet to place, giving it an expected ROI of 5%. The tool also gives this bet a 58% probability to hit. It makes sense given the way the Rams are playing. Stafford is clearly banged up, and he does not have chemistry with Odell Beckham Jr. Stafford will also give the opposing team a couple of plays. If the Cardinals make them and limit their own mistakes, it should be a relatively easy home. However, these divisional games are usually competitive through four quarters.

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NFL Best Bet: Cardinals -2


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Zach Brunner is the founder of FlurrySports and a featured sports betting and fantasy sports expert for numerous outlets. With an education in business, coaching and history education, he has taken a little bit from all of his experiences to give him a well-rounded, unique point of view in the sports industry. Follow him on Twitter @FantasyFlurry to keep up with other things he is doing.

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