There is an interesting Monday Night Football matchup between the Los Angeles Rams and the San Francisco 49ers. These prime-time games have turned in big individual performances. The fact that this is a divisional game should only add to the excitement. Let’s take a look at the best Rams vs. 49ers NFL betting picks for the Week 10 Monday Night Football game, using the Awesemo OddsShopper.
Week 10 NFL Best Bets for Monday Night Football
Los Angeles Rams vs. San Francisco 49ers
Date: Monday, Nov. 15, 2021
Time: 8:15 p.m. EST
Venue: Levi’s Stadium — Santa Clara, Calif.
Coverage: ESPN
Rams vs. 49ers NFL Betting Picks + Odds Shopping
Finding the most profitable NFL betting picks has never been easier. The newly updated OddsShopper tool is like the Amazon of sports betting. Simply filter, sort the page and find the NFL best bets within seconds, as seen below.
Brandon Aiyuk Under 4.5 Receptions (-158, FanDuel)
When sorting OddsShopper by expected win percentage, this prop comes to the top. It has Brandon Aiyuk projected for only 3.1 receptions, giving this prop an 81% chance to hit the under and an expected ROI of 32%. After talking about having his confidence back and having a good discussion with his head coach, Aiyuk seemed to have gotten back to his old self last week. However, this tool clearly expects Aiyuk to be the receiver seeing Jalen Ramsey coverage. If that turns out to be true, then it makes sense for the under to be the more likely outcome.
Cooper Kupp Over 7.5 Receptions (-130, Caesars)
The Rams have been trying to include both Cooper Kupp and Robert Woods in the game plan since they are both great wide receivers. With Woods out for the season with an ACL injury, Kupp should have plays called for him even more often. There is a clear step down in talent from Kupp to Van Jefferson, and Odell Beckham Jr. will need time to learn the offense. Kupp has reception totals of nine, 10, seven and 11 the past four games, and his role should be even larger tonight. OddsShopper gives this reception prop a 55% chance to hit the over, projecting Kupp for 8.3 receptions tonight.
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Matthew Stafford Over 280.5 Yards Passing (-110, PointsBet)
For his career, Matthew Stafford has typically shown up for prime-time games, averaging 290.1 yards. Playing in Detroit for so long, these games were few and far between, so he had to make them count. His success in these late games should have him playing well tonight. He also has passed for 281 or more yards in three straight games. The 49ers front seven could have a good game and limit the rushing attack, but they will struggle to contain Stafford’s arm. OddsShopper gives this passing prop a 57% chance to hit the over, projecting Stafford for 311.8 yards.
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