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How to Bet Chiefs vs. Chargers Week 15 Thursday Night Football

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Thursday Night Football for Week 15 features two AFC West teams battle atop the AFC West, with the Kansas City Chiefs traveling to take on the Los Angeles Chargers. The winner of this game will take the lead in the division and control their own fate the rest of the way. The following Chiefs vs. Chargers NFL betting picks preview will provide the current odds, betting trends, and best NFL bets for the Week 15 Thursday Night Football matchup.

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NFL Best Bets & Odds: Week 15 Thursday Night Football

Kansas City Chiefs vs. Los Angeles Chargers
Date: Thursday, Dec. 16, 2021
Time: 8:20 p.m. EST
Venue: SoFi Stadium — Inglewood, Calif.
Coverage: FOX/NFL Network

The Chiefs are firing on all cylinders, and they are coming off a statement win against the Raiders last week. While the offense still has a couple of moments where they look a little shaky, the defense has come to play. Kansas City has given up single-digit point totals in four of the last five weeks, which is impressive regardless of the opponent. However, they must come to play tonight, facing a team that has played them tougher than anyone over the past few years.

For whatever reason, the Chargers have the Chiefs’ number. In six career games, Patrick Mahomes is averaging only 236.2 yards passing against them. On the Los Angeles side, this was the team that Justin Herbert made his impromptu first start against. He has been solid against the Chiefs, averaging 298 yards passing while throwing eight touchdowns to one interception in his three games. Herbert has also been strong in prime time, leading his team to a 3-1 record, posting 295.5 yards per game, a 116.5 passer rating and totaling 12 touchdowns against one interception in four night games.

Chiefs vs. Chargers Betting NFL Picks + Odds Shopping

Using Awesemo’s OddsShopper tool, we can easily compare the NFL odds for Chiefs vs. Chargers betting across the major sportsbooks. Make sure to check out the OddsShopper tool yourself to get the most up-to-date odds.


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Chiefs vs. Chargers NFL Betting Trends

  • Kansas City is 6-7 against the spread this season.
  • The over is 6-7 for the Chiefs this season.
  • Los Angeles is 7-6 against the spread this season.
  • The over is 6-7 for the Chargers this season.

Chiefs vs. Chargers Betting Stats

  • Kansas City is averaging 27.0 points per game this season (T-No. 8 in the NFL).
  • Kansas City is surrendering 20.6 points per game this season (No. 6 in the NFL).
  • The Chargers are averaging 27.0 points per game this season (T-No. 8 in the NFL).
  • The Chargers are surrendering 25.8 points per game this season (No. 26 in the NFL).

Chiefs vs. Chargers NFL Best Bet

We are using the new Awesemo NFL Betting Model to figure out what the best bet for Thursday Night Football is tonight. According to the model, betting the game total over 52 is the best bet to place, giving it a 63% chance to hit with a 10% ROI. The past two games in this rivalry have been high scoring, with game totals of 59 and 54. Both teams’ offenses have also been playing well, with the Chiefs averaging 32.5 points and the Chargers 33 over their past four games. BetMGM gives the best odds for this bet, at -110.

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Best Bet: Over 52


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Zach Brunner is the founder of FlurrySports and a featured sports betting and fantasy sports expert for numerous outlets. With an education in business, coaching and history education, he has taken a little bit from all of his experiences to give him a well-rounded, unique point of view in the sports industry. Follow him on Twitter @FantasyFlurry to keep up with other things he is doing.

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