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DraftKings NFL DFS Main Slate Cheat Sheet: Week 16 Picks & Projections w/ Alexander Mattison

Nathan Joyce

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Week 16 of the NFL regular season is upon us! We have our NFL DraftKings picks cheat sheet to help you get ready for the main slate on Sunday. As always, Awesemo has you covered from top to bottom with NFL DFS picks today, as well as strategy, advice and how to go about building winning daily fantasy lineups. Our DraftKings NFL DFS cheat sheets will be FREE all season long, with expert NFL DFS Picks from the Awesemo lineup optimizer. As of right now, Alexander Mattison looks like a top play in today’s DraftKings cheat sheet.

Week 16 NFL DFS Optimizer Picks: DraftKings Cheat Sheet

More NFL Daily Fantasy Tools

DraftKings and FanDuel NFL DFS Projections

The NFL DFS Projections below were developed and are maintained by Alex Baker, the No. 1-Ranked Daily Fantasy Sports Player. There are separate tabs containing projected fantasy points for various daily fantasy football sites, including DraftKings, FanDuel, Yahoo and No House Advantage. These DFS projections are updated regularly, including whenever any fantasy football-relevant news breaks.

NFL DFS Rankings

The rankings for fantasy points and value are derived directly from Awesemo’s DFS projections. Roster players with solid value rankings and spend most if not all of your salary. Lineups built using this method will be competitive in tournaments.

NFL DFS Ownership Projections

Initial ownership projections for DraftKings and FanDuel main slates are posted Tuesday night and are updated thereafter when major news breaks. Note that last-minute injury reports will impact not only the injured players’ or their replacements’ ownership projection but can affect overall roster construction and, therefore, the ownership projection for every other player on the slate.


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If you’re interested in other NFL DFS tools for multiple game slates, head over to NFL DFS ownership projections, Awesemo's NFL Data Central, DFS NFL rankings, and DFS NFL stacking. Take a look at our inactives list, NFL depth charts and starting line-ups. View our DraftKings NFL DFS ownership rankings and our FanDuel NFL DFS rankings. We also have showdown projections and NFL DFS showdown ownership projections.

I'm a wannabe athlete whose athletic career ended after a long tenure riding the bench through JV baseball. The fantasy sports and sports betting degen side of me blossomed at age 12 when I found fantasy baseball and football, and led to a 12-year submergence into the poker scene -- I started playing "secret" cash games in my parents' basements by age 14. Luckily, I've finally found what I love to do -- write about "fake sports," which my girlfriend refers to it as, though it only took me until age 30. If you decide you like the words I write and follow me on Twitter (@nd_joyce), I apologize in advance for the copious amounts of dog photos you will see.

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