To cap off this exciting NFL Week 6, tonight features an AFC showdown on Monday Night Football, with the Buffalo Bills taking on the Tennessee Titans. With both teams being the NFL betting favorites to win their divisions, the result of this matchup could have seeding implications down the road. The following Bills – Titans NFL betting picks preview will provide the current odds, betting trends, and best NFL bets for the Week 6 Monday Night Football matchup.
NFL Best Bets & Odds: Week 6 Monday Night Football
Buffalo Bills vs. Tennessee Titans
Date: Monday, October 18, 2021
Time: 8:15 p.m. EST
Venue: Nissan Stadium — Nashville, Tenn.
Coverage: ESPN
Following their Week 1 loss, it has been absolute dominance from the Bills. They have outscored their opponents 156-41 over the past four weeks. The defense is playing well, and Buffalo has found a competent running game — two things the team was missing last season. This looks to be the most complete team in the NFL, and Tennessee will need to play their best game, especially defensively, to win on Monday Night Football.
The Titans continue to get healthier on offense. The receiving corps looks complete yet again, with A.J. Brown and Julio Jones both starting. While that receiving duo should be feared, this team’s identity will still be pounding the ball with Derrick Henry, who has averaged nearly 150 yards rushing the past four games. Defensively, however, Tennessee is bad. They allow 6.2 yards per play, which is tied for the fifth worst in the league.
Bills vs. Titans Betting NFL Picks + Odds Shopping
Using Awesemo’s OddsShopper tool, we can easily compare the NFL odds for Bills vs. Titans betting across the major sportsbooks. Make sure to check out the OddsShopper tool yourself to get the most up-to-date odds.
Bills vs. Titans NFL Betting Trends
- Buffalo is 2-3 against the spread this season.
- The over is 1-4 for the Bills this season.
- Tennessee is 2-3 against the spread this season.
- The over is 1-4 for the Titans this season.
Bills vs. Titans Betting Stats
- Buffalo is averaging 34.4 points per game this season (No. 1 in the NFL).
- Buffalo is surrendering 12.8 points per game this season (No. 1 in the NFL).
- Tennessee is averaging 26.4 points per game this season (No. 8 in the NFL).
- Tennessee is surrendering 26.0 points per game this season (No. 24 in the NFL).
Bills vs. Titans NFL Best Bet
We are using the new Awesemo NFL Betting Model to figure out what the best bet for Monday Night Football is tonight. According to the model, betting the game total under 54.5 is the best bet to place, giving it an expected ROI of 8%. The Bills are running the ball much better than they did last season, while the Titans continue to force feed Henry on the ground. Assuming both things continue to be true tonight, there should be long, methodical drives with the clock continuing to tick. This limits the number of drives and opportunities to score points.
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